We investigate the molecular mechanisms underlying axon growth and pathfinding in higher vertebrates. In particular, we study the roles of cell adhesion molecules (CAMs), cytoskeletal components, and intracellular signalling molecules. Our main model system is the developing visual system of chick and mouse embryo (for details please see: http://www.zoo.uni-heidelberg.de/gep).
The PhD projects will focus on the roles of selected axonal cytoskeletal proteins and CAMs for the formation and navigation of axons. Both projects involve a broad spectrum of state-of-the-art techniques including molecular biology/biochemistry, micro-/nano-technology, in vitro and in vivo live imaging microscopy etc. and ultimately aim at contributing to the development of therapeutic approaches to enhance axon regeneration.
We offer a well equipped department and a variety of on-campus-facilities (imaging centers, e.g.), supportive mentoring, and a stimulating scientific environment. Highly motivated candidates, preferentially with a background in (developmental) neurobiology, are encouraged to apply - also already before having completed the diploma/masters project. Full funding of the positions (salary, consumables, meeting participation etc.) is available for three years.
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